Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (53)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Drickamer, K.
Right arrow Articles by B.Dodd, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Drickamer, K.
Right arrow Articles by B.Dodd, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Glycobiology, 1999, Vol. 9, No. 12 1357-1369
© 1999 Oxford University Press

C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genomesequence

Kurt Drickamera and Roger B.Dodd

Glycobiology Institute, Department of Biochemistry, Universityof Oxford, Oxford OX1 3QU, UK

Protein modules related to the C-type carbohydrate-recognitiondomains of animal lectins are found in at least 125 proteinsencoded in the Caenorhabditis elegans genome. Withinthese proteins, 183 C-type lectin-like domains (CTLDs) have beenidentified. The proteins have been classified based on the overallarrangement of modules within the polypeptides and based on sequence similaritybetween the CTLDs. The C.elegans proteins generallyhave different domain organization from known mammalian proteinscontaining CTLDs. Most of the CTLDs are divergent in sequence fromthose in mammalian proteins. However, 19 show conservationof most of the amino acid residues that ligate Ca2+ toform a carbo­hydrate-binding site in vertebrate C-typecarbohydrate-recognition domains. Seven of these domains are particularly similarin sequence to mannose- and N-acetylglucosamine-binding domainsin the vicinity of this Ca2+ site.

a Towhom correspondence should be addressed at: Department of Biochemistry, Universityof Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 GeneticsHome page
G. L. Wheeler, D. Miranda-Saavedra, and G. J. Barton
Genome Analysis of the Unicellular Green Alga Chlamydomonas reinhardtii Indicates an Ancient Evolutionary Origin for Key Pattern Recognition and Cell-Signaling Protein Families
Genetics, May 1, 2008; 179(1): 193 - 197.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
G. Kulkarni, H. Li, and W. G. Wadsworth
CLEC-38, A Transmembrane Protein with C-Type Lectin-Like Domains, Negatively Regulates UNC-40-Mediated Axon Outgrowth and Promotes Presynaptic Development in Caenorhabditis elegans
J. Neurosci., April 23, 2008; 28(17): 4541 - 4550.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Y. Yu, Y. Yu, H. Huang, K. Feng, M. Pan, S. Yuan, S. Huang, T. Wu, L. Guo, M. Dong, et al.
A Short-Form C-Type Lectin from Amphioxus Acts as a Direct Microbial Killing Protein via Interaction with Peptidoglycan and Glucan
J. Immunol., December 15, 2007; 179(12): 8425 - 8434.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
T. Ishigaki, I. Ohki, N. Utsunomiya-Tate, and S.-i. Tate
Chimeric Structural Stabilities in the Coiled-Coil Structure of the NECK Domain in Human Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 (LOX-1)
J. Biochem., June 1, 2007; 141(6): 855 - 866.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
H. L. Cash, C. V. Whitham, C. L. Behrendt, and L. V. Hooper
Symbiotic bacteria direct expression of an intestinal bactericidal lectin.
Science, August 25, 2006; 313(5790): 1126 - 1130.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
S. Bulgheresi, I. Schabussova, T. Chen, N. P. Mullin, R. M. Maizels, and J. A. Ott
A New C-Type Lectin Similar to the Human Immunoreceptor DC-SIGN Mediates Symbiont Acquisition by a Marine Nematode
Appl. Envir. Microbiol., April 1, 2006; 72(4): 2950 - 2956.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. H. Thomas
Analysis of Homologous Gene Clusters in Caenorhabditis elegans Reveals Striking Regional Cluster Domains
Genetics, January 1, 2006; 172(1): 127 - 143.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Garate, Z. Cao, E. Bateman, and N. Panjwani
Cloning and Characterization of a Novel Mannose-binding Protein of Acanthamoeba
J. Biol. Chem., July 9, 2004; 279(28): 29849 - 29856.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
Y. Adachi, T. Ishii, Y. Ikeda, A. Hoshino, H. Tamura, J. Aketagawa, S. Tanaka, and N. Ohno
Characterization of {beta}-Glucan Recognition Site on C-Type Lectin, Dectin 1
Infect. Immun., July 1, 2004; 72(7): 4159 - 4171.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
D. A. Shagin, E. V. Barsova, E. A. Bogdanova, O. V. Britanova, N. G. Gurskaya, K. A. Lukyanov, M. V. Matz, N. I. Punkova, N. Y. Usman, E. P. Kopantzev, et al.
Identification and characterization of a new family of C-type lectin-like genes from planaria Girardia tigrina
Glycobiology, August 1, 2002; 12(8): 463 - 472.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Bouyain, N. J. Silk, G. Fabini, and K. Drickamer
An Endogenous Drosophila Receptor for Glycans Bearing alpha 1,3-Linked Core Fucose Residues
J. Biol. Chem., June 14, 2002; 277(25): 22566 - 22572.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Sharrow and M. Tiemeyer
Gliolectin-mediated carbohydrate binding at the Drosophila midline ensures the fidelity of axon pathfinding
Development, November 15, 2001; 128(22): 4585 - 4595.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
R. B. Dodd and K. Drickamer
Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity
Glycobiology, May 1, 2001; 11(5): 71R - 79R.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
A. Seppo and M. Tiemeyer
Function and structure of Drosophila glycans
Glycobiology, April 1, 2000; 10(8): 751 - 760.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.