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Glycobiology Advance Access originally published online on September 26, 2003
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Glycobiology, 2003, Vol. 13, No. 12 29G-30G
© 2003 Oxford University Press

GLYCO-FORUM SECTION

Letter to the Glyco-Forum

Biological properties of sulfated fucans: the potent inhibiting activity of algal fucoidan against the human complement system

Bérangère Tissot and Régis Daniel1,

Laboratoire Analyse et Environnement, UMR 8587 CNRS, Université Evry Val d'Essonne, Bd. François Mitterrand, 91025 Evry CEDEX, France

Received on September 5, 2003; accepted on September 10, 2003

The first 10% of the full text of this article appears below.

In this letter we want to point out that the recently published review by Berteau and Mulloy (2003)Go about the biological properties of fucoidan, although well documented, omits any mention of the potent inhibiting activity of this polysaccharide against the human complement system. This activity gives rise to an increasing interest, given the involvement of the complement in numerous pathological processes and the strong demand for efficient anticomplementary molecules.

The complement system is a major component of the immunity and is mainly . . . [Full Text of this Article]


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