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Glycobiology Advance Access originally published online on February 14, 2006
Glycobiology 2006 16(5):82R-90R; doi:10.1093/glycob/cwj080
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© The Author 2006. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

REVIEW

Advancing glycomics: Implementation strategies at the Consortium for Functional Glycomics

Rahul Raman, Maha Venkataraman, Subu Ramakrishnan, Wei Lang, S. Raguram and Ram Sasisekharan1

Biological Engineering Division, Center for Biomedical Engineering, Center for Environmental Health Sciences, Massachusetts Institute of Technology; Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139

1 To whom correspondence should be addressed; e-mail: rams{at}mit.edu

Received on December 21, 2005; revised on January 16, 2006; accepted on January 19, 2006

Glycomics—an integrated approach to study structure–function relationships of complex carbohydrates (or glycans)—is an emerging field in this age of post-genomics. Realizing the importance of glycomics, many large scale research initiatives have been established to generate novel resources and technologies to advance glycomics. These initiatives are generating and cataloging diverse data sets necessitating the development of bioinformatic platforms to acquire, integrate, and disseminate these data sets in a meaningful fashion. With the consortium for functional glycomics (CFG) as the model system, this review discusses databases and the bioinformatics platform developed by this consortium to advance glycomics.

Key words: bioinformatics/CFG/glycan/glycomics


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